• @SolOrion@sh.itjust.works
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    19 hours ago

    Well, generally you’re only supposed to take ~2 tablets at a time, so 10? 40 pills a day is 13,000mg of acetaminophen, or 20,000mg if they’re extra strength.

    That’s, uh, bad. You’re recommended to take under 4000mg per day, so that’d be a bit over a packet? Makes sense to me.

    For the record, mixing two painkillers without consulting a doctor is also usually a bad idea but way fucking less of a bad idea than taking 13000mg of tylenol in a day. Afaik, acetaminophen with other stuff is probably fine but napoxen, ibuprofen, and aspirin all work roughly the same way and shouldn’t be mixed.

    • @Korhaka@sopuli.xyz
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      313 hours ago

      Don’t take my word for it but I think paracetamol and ibuprofen with added codeine can be taken together despite the double codeine as the amount they have is low enough that double is still safe.

      Check with a pharmacist first, dosages are going to vary and I am just some guy on the internet.

    • @wjrii@lemmy.world
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      1119 hours ago

      For the record, mixing two painkillers without consulting a doctor is also usually a bad idea but way fucking less of a bad idea than taking 13000mg of tylenol in a day.

      Basically, if something hurts so much that you might take enough paracetamol/acetaminophen to fuck with your liver then you yes, you should be under a doctor’s care. That said, between my wife and me, we’ve had three or four doctors over the years all be very chill with the idea of alternating Tylenol and Ibuprofen after surgery or the like. I guess they work on such different chemical pathways that they don’t have much interaction potential, and keeping under the daily dose of Tylenol in particular is incredibly important, as we’ve seen in this thread.

      • @Ledericas@lemm.ee
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        28 hours ago

        tyelonol works on the liver, the others like ibuprofen, naproxen,etc works by inhibiting the cox1 and 2 enzymes. of courses take 2 much of the inhibitors is very similar to aspirin, it can prevent clotting(which in itself is a therapeuthic uses for clotting disorders)

      • @SolOrion@sh.itjust.works
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        10 hours ago

        yes, you should be under a doctor’s care.

        That’s not always an option, unfortunately, but it’s definitely accurate.

      • @peoplebeproblems@midwest.social
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        518 hours ago

        They act on different systems, yes, but this is more about the metabolism of each.

        Non-steroidal-anti-inflamatorirs can cause damage to your stomach and kidneys.

        Acetaminophen/Paracetol metabolizes in the liver a similar way alcohol does, and like alcohol has a maximum rate of clearing the toxin.