We could quibble over the definition of “a show” but a good place to start would be:

Big Top Burger

The Gaslight District

MonkeyWrench

Auralnauts’ Larry series

Mummy Joe’s Kid Vampire

Natural Habitat Shorts

Speedoru’s Punch Punch Forever

Space Station Weird by Luke Humphris

Gobelins (entire channel)

DoodletmeGO (ditto)

Bite Shift by Liz & Ivy

Don Hertzfeldt

Lazy Square

Felix Colgrave

Bravest Warriors on Cartoon Hangover

The “5 Second Day” playlist from titmouse studio

Lackadaisy

Otaking (random animations)

Out of Joel Haver’s insane challenge of making 12 feature films in 12 months that nobody watches because they just want the cartoon filter shorts, I loved these two films:

https://www.youtube.com/watch?v=lbZDX_J3nOE

https://www.youtube.com/watch?v=9RS5dUZ2WNg

I liked 2 others, but these were the strongest of the bunch IMO.

Then you’re wtching the wrong kind of atuff on youtube my dude

I can think of a few off hand but the best to come to mind is the dude who did the Astartes videos.